Extraintestinal Crohn’s Disease Mimicking Autoimmune Inner Ear Disease: A Histopathological Approach
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چکیده
Patients with autoimmune inner ear disease develop rapidly progressive sensorineural hearing loss over a period of several weeks or months, often accompanied by vestibular loss. This disease can occur as a distinct clinical entity or in association with an underlying autoimmune disorder. Treatment comprises immunosuppression by corticosteroids, cytostatic drugs or tumor necrosis factor-alpha antagonists. We report histopathological and immunohistochemical findings of the inner ear of a patient with a granulomatous inner ear disease suffering from Crohn’s disease that was nonresponsive to treatment and who underwent surgery for bilateral cochlear implants. DOI: https://doi.org/10.1159/000315063 Posted at the Zurich Open Repository and Archive, University of Zurich ZORA URL: https://doi.org/10.5167/uzh-34825 Published Version Originally published at: Dettmer, M; Hegemann, I; Hegemann, S C A (2010). Extraintestinal Crohn’s Disease Mimicking Autoimmune Inner Ear Disease: A Histopathological Approach. Audiology and Neurotology, 16(1):36-40. DOI: https://doi.org/10.1159/000315063
منابع مشابه
Extraintestinal Crohn's disease mimicking autoimmune inner ear disease: a histopathological approach.
Patients with autoimmune inner ear disease develop rapidly progressive sensorineural hearing loss over a period of several weeks or months, often accompanied by vestibular loss. This disease can occur as a distinct clinical entity or in association with an underlying autoimmune disorder. Treatment comprises immunosuppression by corticosteroids, cytostatic drugs or tumor necrosis factor-α antago...
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